Comparative characteristics of some methods for estimating energy expenditure in critically ill mechanically ventilated patients.

AIM: To compare the energy expenditure (EE) assessed by ventilator-derived carbon dioxide production (EE-VCO2-ventilator) and the energy expenditure calculated from six predictive equations with the gold standard energy expenditure measured with indirect calorimetry (IC) in mechanically ventilated patients.

A genetic-based pairwise trip planner recommender system.

The massive growth of internet users nowadays can be a big opportunity for the businesses to promote their services. This opportunity is not only for e-commerce, but also for other e-services, such as e-tourism. In this paper, we propose an approach of personalized recommender system with pairwise preference elicitation for the e-tourism domain area. We used a combination of Genetic Agorithm with pairwise user preference elicitation approach. The advantages of pairwise preference elicitation method, as opposed to the pointwise method, have been shown in many studies, including to reduce incosistency and confusion of a rating number. We also performed a user evaluation study by inviting 24 participants to examine the proposed system and publish the POIs dataset which contains 201 attractions used in this study.

Ehlers-Danlos Syndrome Type IV - Anaesthetic Considerations.

Ehlers-Danlos syndrome (EDS) is a rare disorder that occurs due to genetic defect in the collagen synthesis. The vascular subtype of EDS (type IV) is defined by characteristic facial features, translucent skin, easy bruising, and spontaneous arterial rupture and visceral perforation of such organs as the uterus and intestines, with possible life-threatening consequences. We report a case of a 15-year-old male patient with no past medical history undergoing emergency laparotomy after a spontaneous sigmoid colon perforation. Post-operatively and during the ICU stay complications developed and several revision operations and invasive procedures were necessary. A chest CT angiography revealed a right subclavian artery aneurysm, which was treated by an endovascular stent grafting. Taking into consideration the family history and clinical presentation EDS type IV was discussed as a possible cause of the patient's condition. DNA analysis confirmed the diagnosis. Due to the lack of evidence-based recommendations the anaesthetic management of these patients is still challenging.